Funded Medical Projects
$70,000 - Halo Therapeutics: HT100 Phase 1/2, Anti Fibriotic agent for the treatment of Duchenne Muscular Dystrophy.
$30,000 – Preparation of the Anti-Fibrotic Halofuginone for use in a multi-center Phase II clinical trial. Halofuginone is an anti-fibrotic and muscle regeneration promoter. To date 1.1 million dollars has been funded to help this project get to phase II clinical trial. Halo Press Release.
$15,000 - DDID #100077 Multi Centered randominzed double blind dose titration. Phase II study in patients in DMD to evaluate efficacy and tolerability of the combination of Ibuprofin and Isosorbide.
$15,000 - DDID #100071 Quercetin - Determining the mechanisms whereby a Quercetin enriched diet interrupts disease process in DMD.
$15,000 - Hugo W. Moser Research Institute at Kennedy Kreiger for Duchenne Muscular Dystrophy Research
$10,000 - Measurement of in vivo respiratory and cardiac function during dietary enrichment in animal models of DMD.
$10,000 – Muscle regeneration available research available with compounds delivered as nutraceutical. Using an unbiased screen a genetic pathway was identified and associated compounds that regenerate muscle in Duchenne Muscular Dystrophy mouse and fly models. Funding will assist in furthering research in this area.
$7,500 - Relaxin: Natural hormone which has the ability to regenerate muscle, reduce scarring, and improve cardiac function
$5,000 - Development of Dystrophin Independent Therapy for DMD.
$5,000 - Superior Mouse Model for DMD drug development.
$2,500 – Evaluation of small compounds that increase Utrophin levels for therapy of Duchenne Muscular Dystrophy. Utrophin is a protein and was found during research into Duchenne's muscular dystrophy. It is believed that producing this protein in the human body will help greatly with those affected by this disease.
$2,000 – The effects of Poloxamer-188 (Carmeseal) on cardiac and skeletal muscle function in MDX mice. Cardiac Function plays an important role in those affected by DMD. Funding will help further research with this drug to see hopeful benefit.
$1,000 – Duchenne Dashboard Phases V and VI. The Duchenne Dashboard allows foundations to co-identify co-understand and co-fund projects in order to conquer Duchenne Muscular Dystrophy. Funding in this area is necessary to maintain upgrades to the Dashboard.